"pearl" > wrote in message ...
> "pearl" > wrote in message news:...
> <..>
> > > > 'The diet reduced low-density lipoprotein (LDL)-cholesterol by
> > > > 29.0% +/- 2.7% (P <.001) ' (in two weeks)
> > > >
http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract
> > >
> > > And his claim was "> 50%". IOW, 172% of the average in that study.
> >
> > The average in the study was a reduction of 29%. JC's was
> > ~50%. IOW, ~11% more than the *two weeks* on the diet.
>
> Correction. That should of course be 21%, not 11%. Still.

Another thing. It was an average 29% reduction in LDL, but,
-50% _total_ cholesterol. Meaning that JC's LDL was reduced
by even more than 50%. Nonetheless, beyond an initial reduction
due to a change in diet, you need to take into account improved
liver function over time (as I've indicated in my first post on this).

Emphasis (*) added to the following;

> Here's another relevant study abstract;
>
> Metabolism 1997 May;46(5):530-7
> Effect of a diet high in vegetables, fruit, and nuts on serum lipids.
> Jenkins DJ, Popovich DG, Kendall CW, Vidgen E, Tariq N,
> Ransom TP, Wolever TM, Vuksan V, Mehling CC, Boctor DL,
> Bolognesi C, Huang J, Patten R.
> Clinical Nutrition and Risk Factor Modification Center, Division
> of Endocrinology, St. Michael's Hospital, Toronto, Ontario, Canada.
>
> We assessed the effect of a diet high in leafy and green vegetables,
> fruit, and nuts on serum lipid risk factors for cardiovascular disease.
> Ten healthy volunteers (seven men and three women aged 33 +/- 4
> years [mean +/- SEM]; body mass index, 23 +/- 1 kg/m2) consumed
> their habitual diet (control diet, 29% +/- 2% fat calories) and a diet
> consisting largely of leafy and other low-calorie vegetables, fruit, and
> nuts (vegetable diet, 25% +/- 3% fat calories) for two 2-week periods
> in a randomized crossover design. After 2 weeks on the vegetable diet,
> lipid risk factors for cardiovascular disease were significantly reduced
> by comparison with the control diet (low-density lipoprotein [LDL]
> cholesterol, 33% +/- 4%, P < .001; ratio of total to high-density
> lipoprotein [HDL] cholesterol, 21% +/- 4%, P X .001; apolipoprotein
> [apo] B:A-I, 23% +/- 2%, P < .001; and lipoprotein (a) [Lp(a)],
> 24% +/- 9%, P = .031). The reduction in apo B was related to
> increased intakes of soluble fiber (r = .84, P = .003) and vegetable
> protein (r = -.65, P = .041). On the vegetable compared with the
> control diet, *the reduction in total serum cholesterol was 34% to 49%
> greater than would be predicted by differences in dietary fat and
> cholesterol.* A diet consisting largely of low-calorie vegetables and
> fruit and nuts markedly reduced lipid risk factors for cardiovascular
> disease. Several aspects of such diets, which may have been consumed
> early in human evolution, have implications for cardiovascular disease
> prevention.'
>
> Publication Types: Clinical trial Randomized controlled trial
> PMID: 9160820 [PubMed - indexed for MEDLINE]

How would you explain that greater than would be predicted
difference, usual suspect?

Take your time.

[my last post for today]