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Mark Thorson Mark Thorson is offline
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Default For Gout sufferers

Sky wrote:
>
> Please be aware that colchicine does have the potential to be lethally
> toxic when too much is taken. And, it doesn't take much. Plus, the
> side effects (for most folks) can be nearly as bad as gout (just depends
> - no pun intended!).


This is a good article on colchicine.

http://www.phc.vcu.edu/Feature/oldfe...olchicine.html

It blocks a fundamental cellular process -- microtubule
assembly. I'm not sure it makes sense to do that for gout.
That's like using nuclear bombs against locusts.

It has a very low therapeutic index -- small difference between
an effective dose and a harmful dose.

http://www.fda.gov/Cder/drug/unappro...chicine_qa.htm