On Jun 25, 9:51*am, ImStillMags > wrote:
> On Jun 24, 10:33*pm, Mark Thorson > wrote:
>
>
>
>
>
> > Cheryl wrote:
>
> > > I take Turmeric supplements.
>
> > Curcumin (the yellow pigment in tumeric) both inhibits
> > P-glycoprotein (the cell membrane protein that transports
> > toxins out of the cell) and activates the steroid and
> > xenobiotic receptor (SXR). *In the short term, it inhibits
> > the clearance of toxins and drugs. *In the long term,
> > it activates at the transcriptional level greater
> > expression of the xenobiotic transporter P-gp and the
> > main metabolizing enzyme in the human body CYP3A4.
> > Oooh! *You don't want that!
>
> > That's why I stopped eating curry completely a few years
> > ago. *If I was ever diagnosed with cancer, I might
> > already be in a state of multidrug resistance (up-regulation
> > of expression of drug clearance enzymes), if I continued
> > the high level of curry consumption I had for many years.
>
> > That's also why I stopped eating Chinese chives. *They
> > contain another modulator of drug clearance.
>
> > Those aren't the only foods that mess around with drug
> > clearance. *Yellow onions and grapefruit also do that.
> > If you're on cancer chemotherapy or a recipient of
> > an organ transplant (and taking the anti-rejection drug
> > cyclosporine), you'll probably be given a list of foods
> > to avoid. *Any complete list will contain all of the
> > foods I mentioned above, plus some herbal remedies such
> > as St. John's Wort. *SJW has caused organ rejection in
> > some people, and failure of birth control drugs in other
> > people because of its powerful up-regulation of the drug
> > clearance enzymes.
>
> Hey Mark......I'm certain that, if you look long enough and hard
> enough at any particular component of any particular food you can find
> a toxin that can possibly do harm.

You're "certain," eh? Do you have a magical unicorn or an oracle?
>
> Personally I don't focus on the possibility of harm simply because of
> all these 'studies'. * By the time you've obsessesd about all of them
> you are down to air and water and both have toxins in them that can
> kill you.

"Studies" by scientists are the way we know things, but I guess you
have a better source. Perhaps your ignoramus sister?
>
> All things in moderation. * *I don't believe anyone eats the amount of
> any particular food on a continuous basis that can actually cause the
> conditions found in these studies.

You "don't believe." Your beliefs do not affect, nor reflect reality.
>
> Seriously, take a couple of steps back and look at the big picture.
> Just sayin.......... *;-)

Pretty much everything you wrote is a load of crap. Conventional
wisdom.

--Bryan